15th World Congress Clinical Nutrition

19th – 22nd September 2010  El Sokhna Resort -  Egypt

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Probiotics: Nutraceuticals with a History and a Future

Robert L Clancy University of Newcastle, Australia

 Probiotics as a product of the food industry, are traditionally considered to be ‘bacteria that are good for you.’ This wide definition has become narrowed to one that considers probiotics to have a particular local and systemic role that involves regulation of mechanisms of mucosal protection. A more descriptive term is ‘immunobiotics’, focussing on driving effective mucosal immunity on one hand, while downregulating damaging hypersensitivity reactions, in particular allergy. The role of the gut flora in maintaining health has been recognised for years; probiotic therapy finds a role in management when this process is defective. This presentation will consider some of the data relevant to mucosal protection, mechanisms whereby probiotics modulate immune mechanisms with a focus on toll-like receptors, as well as practical issues regarding isolate selection, stability and the use of multiple products. Future directions for product development and target disease selection will be discussed


   
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