15th World Congress Clinical Nutrition

19th – 22nd September 2010  El Sokhna Resort -  Egypt

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Effect of Naturo fruit bars on blood glucose levels in patients with type-II

Diabetes mellitus

K Reddy, I Raju, B Giriprasad2, G Lakshminarayanan3, R Chandra Sekhar3, CD Reddy Sugen Life Sciences, Andhra Pradesh ,. Srinivasa Diabetics & MedicalCentreAndhraPradesh, Naturo Food & Fruit Products, Bangalore , India

The effect of Naturo fruit bars (NFB) in altering the key metabolic parameters in type-2 diabetes mellitus was tested in a randomized open-label short-term (2 weeks) and a long-term (12 weeks) clinical trial on healthy volunteers and type-2 diabetics.

Design of the study: In a dose escalation study, 13 healthy volunteers and 10 type-2 diabetics were given 2, 3, 4 fruit bars on day 0, 7 and 14 and blood glucose levels were determined at time ‘zero’ and two hours of consumption of NFB. In the long-term trial, 18 patients of type-2 diabetics consumed two NFB per day for 12 weeks, and blood glucose (fasting and post-prandial), insulin, hemoglobin A1C (HbA1C), lipid profile and adiposity were determined on day ‘zero’ and at the end of twelve weeks.

Results: The short-term study showed that consumption of 2, 3 or 4 NFB did not elevate blood glucose levels in healthy subjects and in type-2 diabetics. Administration of two NFB to type-2 diabetics for 12 weeks did not increase the fasting and post-prandial glucose levels. Other parameters such as cholesterol, HDL cholesterol, LDL cholesterol, triglycerides and body mass index were not altered in type-2 diabetics.

Conclusion The study demonstrates that the NFB did not increase the blood glucose levels and thus can be used as a substitute for healthy food in type-2 diabetics without any undesirable effects.




   
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