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15th
World Congress Clinical Nutrition
19th
– 22nd September 2010 El Sokhna Resort - Egypt
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Copyright © 2010.
WCCN2010.COM
All rights reserved |
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Functional foods and
nutraceuticals and brain functions
AK Singh, R B Singh,M Moshiri,
Fabien De Meester, L Juneja.
Moradabad, India, TTI ,Krakow,Poland,
Taiyo Kagaku, Yokkaichi, Japan
icn2005@sancharnet.in
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The seven country study showed that the mortality due to coronary artery
disease was continuous and graded
with rise in serum cholesterol.
However, there was variation in
mortality rates in different
countries at the same levels of
serum cholesterol. It is possible
that antioxidants; flavonoids,
vitamins A,E,C , minerals; copper,
zinc, selenium and chromium and w-3
fatty acids present in the diet may
explain, the cause of the variation
in risk of coronary artery disease
and cancer mortality in various
countries. These nutrients are also
important for neuronal
dysfunctions.Indian diets are rich
in antioxidant vitamins A,E,C and
betacarotine and various flavonoids
and the consumption of fruits,
vegatables and legumes varies
between 50-500g/day,( average
200g/day),according to five city
study. The main sources of
antioxidants in the diets are
fruits, vegetables, oils, sprouted
seeds, and herbs. In Kerala, coco
nuts are rich sources of tocoferols
and tocotrenols and fish is rich in
selenium and coenzyme Q10.If we
consider, only these two foods to
assess antioxidant in the diets, the
contents appear to be enough to
prevent cardiovascular disease. Fish
is also a rich source of w-3 fatty
acids and amino acids.These agents
present in the foods may be called
nutraceuticals because they are now
available in the market as
therapeutic agents. The content and
concentration of particular
nutrients can be altered by feeding
nutrient rich feeds to animals and
by enhancing the nutrients in the
soil which is a feed for plants.
Genetic engineering and plant
breeding may be also used to enhance
the nutrient content of plant foods.
While Dr Sim from Canada has
increased the ω-3 fatty acid content
of hen,s eggs, by feeding flax
seeds, Kang has developed ω -3 fatty
acid rich mice by genetic
manipulations (Nature 2002).
Magnesium, potassium, sodium and
calcium present in the foods can
influence AT-pases and related ion
channels present in cell membranes.
Coenzyme Q10 and carnitine are rich
in muscles including cardiac muscles
and can be enhanced by regular
physical activity and therapeutic
supplementation. We have been using
several of these nutrients and
nutraceuticals for treatment of
dementia as well as for degenerative
brain diseases, apart from their use
CVDs, in clinical practice.
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