15th World Congress Clinical Nutrition

19th – 22nd September 2010  El Sokhna Resort -  Egypt

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Vascular Variability Anomaly, VVA versus Vascular Variability Disorder, VVD in Poland

Agnieszka Wilczynska1, Fabien De Meester1,2, Germaine Cornélissen3, Ram B Singh4, Franz Halberg3. 1Tsim-Tsoum Inst, Krakow, Poland; 2Columbus Paradigm Inst, Waterloo, Belgium; 3Halberg Chronobiology Center, Univ Minnesota, MN, USA; 4Halberg Hospital & Research Inst, Moradabad, India.


Aim. To distinguish physiologic responses to life events from a disorder by chronobiologically interpreted C-ABPM, using the sphygmochron, a monitoring profile over time with a computer comparison by reference to data from clinically healthy gender- and age-matched peers.

Background. A series of consensus meetings suggested that the cuff in the care provider's office is best replaced by a C-ABPM at home (1, 2), if a number of VVDs are not to be missed in a likely considerable fraction of the population of people already recognized to have high blood pressure, whether or not they are treated for this condition which is but one of several VVDs.

Results. Results from self-monitoring by a 43-year old woman based on a 6-day profile are summarized in the sphygmochron of Figure 1 (top), showing in bold the diagnosis of a blood pressure overswing. Continued monitoring was indicated and revealed, by a sequential test (3), the transient nature of the condition, as summarized in Figure 2 (bottom).

Discussion and Conclusion. Continued monitoring for strain assessment is indicated for everyone in order to "Know thyself", likes and dislikes, as well as to ascertain that VVAs are not treated as VVDs.

References
1. Halberg F, Cornélissen G, Otsuka K, Siegelova J, Fiser B, Dusek J, Homolka P, Sanchez de la Peña S, Singh RB, BIOCOS project. Extended consensus on need and means to detect vascular variability disorders (VVDs) and vascular variability syndromes (VVSs). Geronto-Geriatrics: Int J Gerontology-ChronomeGeriatrics 2008; 11 (14): 119-146.

2. Halberg F, Cornélissen G, Otsuka K, Katinas GS, Schwartzkopff O, Halpin C, Mikulecky M, Revilla M, Siegelova J, Homolka P, Dusek J, Fiser B, Singh RB. Chronomics* (*the study of time structures, chronomes) detects altered vascular variabilities constituting risks greater than hypertension: with an illustrative case report. In: Mitro P, Pella D, Rybar R, Valocik G, editors. Proceedings, 2nd Congress on Cardiovascular Diseases, Kosice, Slovakia, 25-27 April 2002. Bologna: Monduzzi Editore; 2002. p. 223-258.

3. Cornélissen G, Halberg F, Hawkins D, Otsuka K, Henke W. Individual assessment of antihypertensive response by self-starting cumulative sums. J Medical Engineering & Technology 1997; 21: 111-120.





   
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